Methenolone Enanthate, also commonly referred to as methenolone enanthate, is an AAS or androgen and an anabolic steroid distributed under Nibalinjection and Primobolan Depot. This medicine is used to treat anemia or mainly bone marrow failure. This is an inter-muscle injection, and people can take this injection directly into the muscles. Initially, it was used extensively, but the drug has previewed some complications which have led to its discontinuation and thus is not available anymore. A similar oral pill or medicine, methenolone acetate, is available with the same composition.

Methenolone Enanthate has side effects like acne, voice changes, enhanced sexual urge, and increased hair growth. Synthetic androgen is also an anabolic steroid; thus, androgen receptor has agonized, which are natural androgen targets such as testosterone and dihydrotestosterone (DHT). It has some average anabolic and androgenic effects, but there is no risk of damage in the liver, or estrogenic effects have been found as side effects of this medicine. It is a Methenolone ester, besides being a source of the prodrug of Methenolone, which aids the body's metabolism and has long-lasting positive effects.

This drug was introduced in the medical field in 1962. This drug can enhance mental and physical performance, and people can also use this drug without a prescription. Non-medical use is generally considered illegal since the drug is a controlled substance in most countries. There are few countries, such as Spain and Turkey, where this drug is available in the open markets.

Pharmacology:

  1. Pharmacodynamics - Since it is one of the derivatives of DTH, the dynamic form of Methenolone is not aromatized. Thus there are no estrogenic side effects like gynecomastia that can be found. Methenolone is anti-gonadotropic as an AAS and, therefore, can negatively impact the area around the hypothalamic-pituitary-gonadal axis. It also causes hypogonadism as well as infertility, which is reversible.
  2. Pharmacokinetics - MethenoloneEnanthate enjoys a biological half-existence of 10.5 days, aided by intramuscular injection.


History: 

This drug was first introduced in the famous landscape of the United States in 1962 for medical use under Nibal Depot. Afterward, it was discontinued and banned, and circulation was stopped in the US. Then it was re-launched between the 1960s and 70s under the regimen of Primobolan Depot and marketed in Europe.

For its impact on enhanced physical efficiency, numerous sports practitioners have been known to fall back upon this drug. For countries with Methenolone Enanthate banned, it has led to vast uproars of using banned substances for added efficiency and physical prowess. But, even in the US and the surrounding countries,e numerous reports of this drug being used illicitly, as it has not yet received proper or appropriate governmental approvals. It is usually consumed by other steroids and is not a very potent supplement. Also, it is generally preferred to be taken via injection than orally. The injection provides enhanced bioavailability and is a preferred option for many people due to its cost-effectiveness.